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We Are Solutions...On Demand
Item #: 550-11
Form:
8M Urea, 50mM Tris-HCl, 15mM beta-mercaptoethanol, 1mM EDTA
Product Name:
Troponin I
Protein Conc:
>0.50 mg/mL (A280)
Purity:
>/= 98% by SDS-PAGE
Storage:
-20 C
Source:
Human Heart
Synonyms:
Tn-I, hTn-I
CAS Number:
77108-40-8
UNSPSC code:
51131907
Catalogue Number:
550-11
Expiration:
2 years
Molecular Weight:
~24,000
pH:
7.4 +/- 0.1
Lee Biosolutions supplies human cardiac marker TROPONIN I in research and bulk quantities for IVD Manufacturers.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Other Cardiac Markers Offered:
190-24 - Human Heart Creatine Kinase MB
550-11 - Human Heart Troponin I
550-21 - Human Heart Troponin T
550-40 - Human Heart Troponin C
431-11 - Human Heart Myoglobin
Current studies show that Troponin I is a part of the troponin complex. Troponin I binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Human Troponin is a family of proteins (Troponin I, T and C) found in skeletal and heart muscle fibers; cardiac Troponin helps muscles contract. Certain subtypes of human troponin (cardiac troponin I and T) are very sensitive and specific indicators of damage to the heart muscle myocardium)
Lee Biosolutions, Inc specializes in the development and purification of high quality BioMarkers for the Immunodiagnostic, clinical diagnostic and pharmaceutical industry worldwide.
