Featured Product: Pregnant Mare Serum Gonadotropin (PMSG)

Lee Biosolutions is the leading supplier of Pregnant Mare Serum Gonadotropin (PMSG) for research and diagnostic manufacturing.

Custom preparations, technical support, bulk quantities, and aliquoting available. Email info@leebio.com for more details.

Pregnant mare serum gonadotropin (PMSG) is a glycoprotein hormone synthesized in the domestic horse placenta. Commercial preparations are isolated from the serum of pregnant mares. The hormone is a dimer of non-covalently associated alpha and beta subunits. It is a unique member of the gonadotropin family in that it contains high levels of FSH and LH activity[i]. Its ability to stimulate ovulation is determined in a bioassay, and the results are expressed as international units (IU)[ii]. PMSG that has been purified to homogeneity has approximately 16,000 IU/mg protein[iii]. PMSG may be used to induce ovulation in livestock prior to artificial insemination.

[i] Moore, W.T., Jr. and D.N. Ward, JBC 255, 6923 (1980)

[ii] Cole, H.H. and J. Erway, Endocrinology 29, 514 (1941)

[iii] Gospodarowicz, D. and H. Papkoff, Endocrinology 80, 699 (1967)