Thyroid Stimulating Hormone (TSH)

Catalogue Number: 996-50
Description
Availability Discontinued - See 996-51
Product Name Thyroid Stimulating Hormone
Source Human Pituitary Glands
Catalogue Number 996-50
Form Lyophilized
Purity > 50% (HPLC)
Activity > 5 IU/mg
Contaminants All contaminants are < 5.0% (w/w)
FSH: < 75 IU/mg
hGH: < 0.02 mg/mg
LH: < 170 IU/mg
PRL: < 0.02 mg/mg
Reconstitution Neutral pH buffer of choice. Avoid extreme high and low pH
Formulation Lyophilized from 50 mM ammonium bicarbonate
Recertification 5 years
Storage -20°C
Synonyms TSH, Thyrotropin
Molecular Weight 28,000
Overview

Lee Biosolutions is the leading supplier of THYROID STIMULATING HORMONE (TSH) for clinical research and IVD manufacturing.

FOR LABORATORY AND MANUFACTURING USE ONLY AND NOT FOR USE IN HUMANS

Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta.

The TSH test is often the test of choice for evaluating thyroid function and/or symptoms of hyperthyroidism or hypothyroidism. It is frequently ordered along with or preceding a T4 test. Other thyroid tests that may be ordered include a T3 test and thyroid antibodies (if autoimmune-related thyroid disease is suspected).

according to Labtest online: A high TSH result often means an underactive thyroid gland that is not responding adequately to the stimulation of TSH due to some type of acute or chronic thyroid dysfunction. Rarely, a high TSH result can indicate a problem with the pituitary gland, such as a tumor producing unregulated levels of TSH. A high TSH value can also occur when someone with a known thyroid disorder or who has had their thyroid gland removed is receiving too little thyroid hormone medication.

A low TSH result can indicate an overactive thyroid gland (hyperthyroidism) or excessive amounts of thyroid hormone medication in those who are being treated for an underactive (or removed) thyroid gland. Rarely, a low TSH result may indicate damage to the pituitary gland that prevents it from producing adequate amounts of TSH.

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