Alpha-2 Macroglobulin (A2M)

Catalogue Number: 111-11
Product Name Alpha-2 Macroglobulin
Source Human Plasma
Catalogue Number 111-11
Form Lyophilized
Purity > 95% (SDS-PAGE)
Protein Reported in mg/vial (A280, E0.1%=0.81)
Formulation Lyophilized from 0.03 M sodium phosphate, with 1 mg glycine/mg A2M as a preservative.
Reconstitution 1 mg A2M/mL H2O
Storage 2-8°C
Recertification 4 years
Molecular Weight 725,000
Synonyms Alpha-2-M, A2M, AMG
Gene Synonyms A2MD, CPAMD5, FWP007, S863-7
Gene ID 2

Lee Biosolutions produces human serum Alpha-2 Macroglobulin (A2M) for research and diagnostic manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

A2M is a large plasma protein found in the blood and is produced by the liver. It is a major component of the alpha-2 band in protein electrophoresis. Levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins.

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter, inhibiting many proteases, including trypsin, thrombin and collagenase, and is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

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111-11-1 $ 194.00 1 mg
111-11-10 $ 1,640.00 10 x 1 mg