Thyroglobulin (Tg)

Catalogue Number: 528-11
Product Name Thyroglobulin
Source Human Thyroid Gland
Catalogue Number 528-11
Purity > 96% (Native PAGE)
Form Lyophilized
Protein Reported in mg/vial (A280, E0.1%=1.04)
Formulation Lyophilized from 20 mM ammonium bicarbonate. May contain traces of buffer salts.
Appearance White to off-white powder
Reconstitution Use of a phosphate buffer, pH > 7.0 containing 0.15 M sodium chloride.
Pairing Information Capture Ab: 528-14 - anti-Human Thyroglobulin Monoclonal Antibody
Detection Ab: 528-15 - anti-Human Thyroglobulin Monoclonal Antibody
Antigen: 528-11 - Thyroglobulin from human thyroid gland
Storage 2-8°C
Recertification 5 years
Infectious Disease Testing Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV, HBsAg and Syphilis by FDA approved methods.
Molecular Weight 660,000
Synonyms Tg
CAS Number 9010-34-8
Accession No P01266
Gene TG

Lee Biosolutions is the leading supplier of human Thyroglobulin (Tg) for clinical research and diagnostic manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Thyroglobulin is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland and was referred to as a "colloid". Human Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine.

Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against human Thyroglobulin (Tg). Human Thyroglobulin specific antibodies help in the diagnosis of these diseases, but they also may be present in apparently healthy euthyroid individuals.

Human Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and levels in the blood can also be elevated in cases of Graves disease.

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528-11-1 $ 118.00 1 mg
528-11-10 $ 408.00 10 mg
528-11-100 $ 2,879.00 100 mg