Thrombin

Catalogue Number: 528-50
Description
Product Name Thrombin
Source Bovine Plasma
Catalogue Number 528-50
Purity Purified
Form Lyophilized
Activity 50 - 150 US U/mg
Protein 0.40 - 0.75 mg protein/mg (Biuret)
Specific Activity 90 - 250 US U/mg protein
Moisture Content < 5% (Loss on Drying)
pH 6.5 - 7.5 (1% solution)
Formulation Lyophilized powder containing glycine and sodium chloride.
Reconstitution Solubilize and dilute with 0.9% sodium chloride.
Storage -20°C
Recertification 3 years
Molecular Weight 36,000
Synonyms fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin
Country of Origin United States of America
CAS Number 9002-04-4
E.C. Number 3.4.21.5
Overview

Lee Biosolutions producer and supplier of bovine Thrombin, medical research of proteolytic enzymes and manufacturing of defibrinating human plasma and serum free media component.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Bovine Thrombin EC 3.4.21.5 (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. Bovine Thrombin is a serine protease that converts fibrinogen into fibrin.

Bovine Thrombin used as a reagent, Thrombin has proven useful in the laboratory evaluation of many fibrinogen(s)

Our customers use Bovine Thrombin to defibrinate human plasma, producing serum matrixes to be used as controls and standards. Bovine Thrombin High specific material Cat. NO: 528-50 available (> 2000 U/mg protein) is used to cleave r-fusion proteins containing a thrombin site for removal of affinity tags as well as certain diagnostic pharmaceutical applications.

Thrombin promotes chemotaxis in monocytes, neurite retraction in neuron Thrombin serves as a potent mitogenic agent in fibroblast growth and functions as a serum-free media component for several cell lines

Bovine Thrombin is a multifunctional proteolytic enzyme which acts both specifically and non-specifically with several proteins, cells, surfaces, and other molecules. Bovine Thrombin(s) essential role in the clotting process has been well characterized where it converts fibrinogen, a soluble plasma glycoprotein, to an insoluble protein gel called fibrin, the essential component of the blood clot.

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SKU PRICE (USD) UNIT QTY
528-50-25 $ 105.00 25 kU
528-50-100 $ 248.00 100 kU
528-50-500 $ 717.00 500 kU