Creatine Kinase BB (CK-BB)
|Product Name||Creatine Kinase BB|
|Activity||> 100 U/mg (Dimension® Clinical Chemistry System)|
|Protein||> 0.6 mg protein/mg (Coomassie)|
|Specific Activity||Reported in U/mg protein|
|Isoenzyme Content||CK-BB: > 95% (Helena QuickGel® CK)
CK-MB: < 3%
CK-MM: < 3%
|Unit Definition||One Unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute @ 37°C. Measured at 340 nm as one equimolar amount of NADH produced by a coupled reaction.|
|Solubility||Clear, light yellow solution (1 mg/mL saline)|
|Form||Lyophilized from 10 mM tris-succinate, 2 mM DTT, 2 mM EDTA, pH 6.5.|
|Synonyms||CPK-1, CKBB isoenyzme, CK-BB|
Diagnostic Controls, Calibrators & Standards
Lee Biosolutions is the leading producer of porcine Creatine Kinase BB (CK-BB) Isoenzyme for clinical research diagnostic manufacturing. Porcine CKBB performs the same as human CKBB in diagnostic kits.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Creatine Kinase BB is concentrated in the brain and lungs Because the CKBB isoenzyme, CPK-1 isoenzyme is predominately found in the brain and lungs, injury to either of these organs (for example, stroke or lung injury due to a pulmonary embolism) are associated with elevated levels of this isoenzyme.