Pepsinogen II (PGII, PGC)

Catalogue Number: 440-52
Description
Product Name Pepsinogen II
Source Human Gastric Mucosa
Catalogue Number 440-52
Purity > 90% (SDS-PAGE)
Purity Note Typically > 96% (SDS-PAGE)
Form Lyophilized
Protein Reported mg protein/vial (A280nm, E0.1%=1.43)
Specific Activity > 1,000 U/mg protein (After activation)
Unit Definition One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Appearance White to off-white powder
Solubility Clear, colorless liquid (1 mg/mL 0.02 M tris-cholride, pH 8.0)
Reconstitution After reconstitution maintain at or above pH 8.0 to avoid activation.
Formulation Lyophilized from tris-chloride, pH 8.5
Related Products 440-50 - Pepsinogen I from human gastric mucosa
441-10 - Pepsin 1:10,000 from porcine gastric mucosa
435-10 - Mucin from porcine gastric mucosa
Recertification 3 years
Storage -20°C
Infectious Disease Testing Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods.
Molecular Weight 40,600
Synonyms Pepsinogen C, PG II, PGC, Gastricsin, Pepsinogen 2
E.C. Number 3.4.23.3
Gene PGC, RP11-298J23.1, PEPC, PGII
Gene ID 5225
Accession No P20142
Overview

Lee Biosolutions is the leading producer and supplier of Human Pepsinogen II/C antigen as a stomach gastric cancer marker for medical research, clinical and diagnostic manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of porteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.

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SKU PRICE (USD) UNIT QTY
440-52-0.1 $ 272.00 100 ug
440-52-1 $ 629.00 1 mg
440-52-10 Inquire 10 x 1 mg
Representative SDS-PAGE & WB - 440-52