Pepsinogen II (PGII, PGC)
|Product Name||Pepsinogen II|
|Source||Human Gastric Mucosa|
|Purity||> 90% (SDS-PAGE)|
|Protein||Reported mg protein/vial (A280, E0.1%=1.48)|
|Specific Activity||> 1,000 U/mg protein (After activation)|
|Unit Definition||One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.|
|Identity||Confirmed by Western Blot|
|Form||Lyophilized from tris-chloride, pH 8.5|
|Solubility||Clear, colorless liquid (1 mg/mL saline)|
|Synonyms||Pepsinogen C, PG II, PGC, Gastricsin, Pepsinogen 2|
|Gene||PGC, RP11-298J23.1, PEPC, PGII|
Lee Biosolutions is the leading producer and supplier of Human Pepsinogen II/C antigen as a stomach gastric cancer marker for medical research, clinical and diagnostic manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of porteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.