Pepsinogen II (PGII, PGC)

Catalogue Number: 440-52
Product Name Pepsinogen II
Source Human Gastric Mucosa
Catalogue Number 440-52
Purity > 90% (SDS-PAGE)
Purity Note Typically > 96% (SDS-PAGE)
Form Lyophilized
Protein Reported mg protein/vial (A280nm, E0.1%=1.43)
Specific Activity > 1,000 U/mg protein (After activation)
Unit Definition One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Appearance White to off-white powder
Solubility Clear, colorless liquid (1 mg/mL 0.02 M tris-cholride, pH 8.0)
Reconstitution After reconstitution maintain at or above pH 8.0 to avoid activation.
Formulation Lyophilized from tris-chloride, pH 8.5
Related Products 440-50 - Pepsinogen I from human gastric mucosa
441-10 - Pepsin 1:10,000 from porcine gastric mucosa
435-10 - Mucin from porcine gastric mucosa
Recertification 3 years
Storage -20°C
Infectious Disease Testing Negative or non-reactive at the donor level for anti HIV 1 and 2, anti HCV, syphilis (RPR) and HBsAg by FDA approved methods
Molecular Weight 40,600
Synonyms Pepsinogen C, PG II, PGC, Gastricsin, Pepsinogen 2
E.C. Number
Gene PGC, RP11-298J23.1, PEPC, PGII
Gene ID 5225
Accession No P20142

Lee Biosolutions is the leading producer and supplier of Human Pepsinogen II/C antigen as a stomach gastric cancer marker for medical research, clinical and diagnostic manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available, email for more details.

Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of porteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.

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440-52-0.1 $ 376.00 100 ug
440-52-1 $ 870.00 1 mg
440-52-10 Inquire 10 x 1 mg
Representative SDS-PAGE & WB - 440-52