Haptoglobin 1-1 (Hp1-1)

Catalogue Number: 330-12
Description
Product Name Haptoglobin 1-1
Source Human Plasma
Catalogue Number 330-12
Purity > 95% (SDS-PAGE)
Form Lyophilized
Protein Reported in mg/vial (A278 E0.1%=1.20)
Genotype 1-1
Appearance White to near white
Reconstitution Centrifuge briefly prior to opening and reconstitute with deionized water in the provided container for full recovery. Aliquot and freeze at -20°C after reconstitution.
Related Products 330-11 - Haptoglobin antigen
330-13 - Haptoglobin 2-2 antigen
Storage -20°C
Recertification 2 years
Molecular Weight 86,000
Synonyms Hp1-1
Overview

Lee Biosolutions is the leading manufacturer of Human Haptoglobin for research and diagnostics.

Custom preparations, technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.

In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen).

In clinical settings, the haptoglobulin assay is used to screen for and monitor intravascular hemolytic anemia . In intravascular hemolysis, free hemoglobin will be released into circulation and hence haptoglobin will bind the Hb. This causes a decline in Hp levels. Conversely, in extravascular hemolysis the reticuloendothelial system, especially splenic monocytes, phagocytose the erythrocytes and hemoglobin is not released into circulation; serum haptoglobin levels are therefore normal.

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SKU PRICE (USD) UNIT QTY
330-12-1 $ 166.00 1 mg
330-12-10 Inquire 10 mg
330-12-100 Inquire 100 mg